From:
https://en.wikipedia.org/wiki/New_Venture_Gear
"6 =
Computer-controlled multi-plate wet clutch"
If you keep everything from the donor and figure out a way to mount the buttons that tell the computer to shift into various modes, it can work as well as it did in the Chevy. Although, you may run into some issues if the computer needs ABS sensors to control the actuation of the clutch. Without the ABS sensors, the computer can't tell when it needs to engage anything. So you'd probably end up with what amounts to an open differential inside the transfer case.
A 241c doesn't have any of that. It has a manual shift lever that is easier to get working and bolts right up.
I do like that the 246 offers a full time 4HI mode as well as a part time 4HI mode. And being able to just hit a button on the dash would be nice. But if I were doing an LS swap, I'd find a Jeep NP242 and adapt it to the Chevy transmission (easy). That's a manual shift version that gives me full and part time 4HI options without having to worry about everything else.
If I were doing a body swap on to a Chevy frame, I would consider the 246. The Chevy frame and drivetrain would supply all of the wheel speed sensors and everything else that came with the whole system.